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Article
January 1954

OCULAR ANTIBIOTIC-PRODUCING BACTERIA IN NORMAL EYES AND IN CONJUNCTIVITIS

Author Affiliations

NEW YORK
From the Departments of Ophthalmology and Bacteriology, Columbia University College of Physicians and Surgeons, and the Institute of Ophthalmology, Presbyterian Hospital.

AMA Arch Ophthalmol. 1954;51(1):7-14. doi:10.1001/archopht.1954.00920040009002
Abstract

ANTIBIOTIC-producing strains of bacteria of the normal flora of various tissues of humans have been found to be very common in recent years. The intestinal tract,* eye,4 nasopharynx,† skin and oral cavity ‡ have proved rich in such microorganisms. The antibiotic activities of the enteric bacteria have been most intensively examined. Suggestive evidence that such inhibitory strains may be related to recovery from bacillary dysentery has been obtained.§ A previous paper from this laboratory4 has described some rather striking general analogies between the situation in the intestinal tract and the ocular flora with respect to such bacterial inhibitors. The present report summarizes the survey findings relating such antibiotic-producing strains to the presence of clinical conjunctival inflammation in the groups examined previously.

MATERIALS AND METHODS  The subjects employed in this study were inmates of a New York state institution for the feebleminded.∥ They were of either sex, from 2

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