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Article
June 1954

RELATION OF TONOGRAPHY TO PHASIC VARIATIONS OF INTRAOCULAR PRESSURE

Author Affiliations

NEW YORK
From the Glaucoma Clinic, Institute of Ophthalmology, London, Director of Research, Sir Stewart Duke-Elder; and from the Institute of Ophthalmology of the Presbyterian Hospital, New York.

AMA Arch Ophthalmol. 1954;51(6):740-749. doi:10.1001/archopht.1954.00920040750002
Abstract

THERE ARE many reports in the literature concerning the spontaneous diurnal changes in the intraocular pressure of both normal and glaucomatous eyes. In the last few years the most notable studies on this subject took place at the Institute of Ophthalmology in London * and were reviewed in an excellent paper by Sir Stewart Duke-Elder.3 The workers here studied both the chronic simple and the congestive type of glaucomatous eyes and noted marked variations in the intraocular pressure over 24-hour periods. Since their studies appeared, Grant † has published the results of his work on aqueous humor dynamics, by a method which is commonly known as the aqueous outflow test, or tonography. Since the cause of the spontaneous changes in the intraocular pressure is not well understood, it was thought that a correlation of Grant's † aqueous outflow test with the diurnal intraocular pressure changes might shed some light on

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