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Article
November 1954

USE OF P32 AS AN AID IN DIAGNOSIS OF INTRAOCULAR NEOPLASMSFurther Observations

Author Affiliations

PHILADELPHIA
From the Research Department, Radioactive Isotope Division, Wills Eye Hospital.

AMA Arch Ophthalmol. 1954;52(5):741-750. doi:10.1001/archopht.1954.00920050747009
Abstract

IN A PREVIOUS paper1 a test using radioactive phosphorus for the detection of intraocular neoplasms was described. The test consisted of injecting 500 μ of P32 intravenously. One hour later counts were taken at the limbus of the normal eye in positions 12, 3, 6, and 9 o'clock. The counter was placed as close to the lesion as possible in the pathologic eye. These counts were recorded as the number per minute.

The limbus was selected as a point of reference as opposed to corresponding points of the globe, for such counts showed less variation with the above technique. This point is stressed, for unless the area over the limbus is used as reference points the results are not consistent. From the data obtained with this technique the following conclusions were reported.

  1. Neoplasms will concentrate P32 in amounts significantly increased over that of normal tissue, and this

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