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Article
January 1955

TREATMENT OF HERPES ZOSTER OPHTHALMICUS WITH CORTISONE OR CORTICOTROPIN

Author Affiliations

Philadelphia
From the Department of Ophthalmology, Hospital of the University of Pennsylvania.

AMA Arch Ophthalmol. 1955;53(1):38-44. doi:10.1001/archopht.1955.00930010040004
Abstract

THIS PAPER presents observations on the treatment of herpes zoster ophthalmicus in 11 patients, all of whom had ocular involvement, by cortisone or corticotropin given systemically. Relief of pain was generally prompt. Striking improvement was usually noted in the ocular lesions. Final visual results were highly encouraging.

From 1937 to 1945, our results had been extremely discouraging in this type of disease. Partial or complete loss of vision, as a result of secondary glaucoma or corneal opacity, was not infrequent. In 1945, in view of the excellent results reported by Friedenwald1 and Gundersen,* we began to employ immune serum therapeutically, with what seemed to be a more favorable outcome. In a group of patients, comparable in size to our present series, no impairment of vision resulted. The treatment of herpes zoster ophthalmicus with immune serum, however, involves certain difficulties. Frequent transfusions are necessary, necessitating a number of donors, who

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