For many years ophthalmic surgeons have been utilizing germicidal solutions in attempts to sterilize their instruments. The fact that the cutting edges of the instruments are not injured by these solutions has popularized their use. The reliability as sterilizers has recently been questioned, however.
It is essential at the time of an operative procedure that the surgeon's instruments be as sharp as they were prior to sterilization. Autoclaving is an unequivocal method of achieving sterility and is adequate for the instruments used in general surgery. Unfortunately, however, autoclaving may cause some deterioration of the sharpness of the delicate instruments used in ophthalmic surgery. Another certain way of achieving sterilization is by means of dry heat. The disadvantage of this method is the length of time it takes, i. e., the time required to heat an oven to 160 C, plus the sterilizing time of two hours at that temperature. This
RIEGELMAN S, VAUGHAN DG, OKUMOTO M. Evaluation of the Sporicidal Activity of Post's Sterilizing Solution. AMA Arch Ophthalmol. 1955;53(6):847-851. doi:10.1001/archopht.1955.00930010855010