Cotton-wool opacities of the retina occur in a number of diseases. They correspond microscpically to agglomerates of cytoid bodies in the nerve fiber layer of the retina.
However, no description of such lesions in Hodgkin's disease has been yet reported in the literature. In a case of uveitis associated with Hodgkin's disease, Kamellin (1944) observed in the macular regions large grayish spots and at the periphery of the retina numerous small white spots "comparable to miliary tubercules." Nothing in the author's description seems to be similar to cottonwool opacities.
Report of a Case
The patient is a 31-year-old woman without previous significant disease.In January, 1951, she presented disseminated adenopathies.In December, 1951, a blood examination disclosed a hypochromic anemia. The patient complained of asthenia, and during the following months she had febrile episodes.She was admitted to the University medical department (Prof. P. Govaerts) on May 16, 1952, with
GEERTRUYDEN MB. Retinal Lesions in Hodgkin's Disease. AMA Arch Ophthalmol. 1956;56(1):94-99. doi:10.1001/archopht.1956.00930040102011