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April 1957

Retinitis Pigmentosa with Normal Electroretinogram

Author Affiliations

U. S. Army; Washington, D. C.
Walter Reed Army Medical Center: Ophthalmology Service, Walter Reed Army Hospital (Lieut. Col. Skeehan); Ocular Research Unit, Walter Reed Army Hospital (Lieut. Col. Passmore); Walter Reed Army Institute of Research (Dr. Armington).

AMA Arch Ophthalmol. 1957;57(4):536-538. doi:10.1001/archopht.1957.00930050548007

The case of a 17-year-old Negro youth who exhibited classical clinical retinitis pigmentosa but showed an eletroretinogram (ERG) of normal response and contour is here reported.

The most striking changes in the ERG are found in retinitis pigmentosa,1-3 the response of the retina being totally absent or extinguished even in the early stages of development. A few subnormal ERG's have been described in retinitis pigmentosa,4 but these were elicited only under favorable conditions. In congenital nyctalopia only the photopic, or cone, components are apparent.5

Report of a Case  The only significant items in the patient's history were difficulty with night vision and somewhat less difficulty with day vision. The patient's two sisters have normal vision. Neither the father nor the mother are affected. Neither of the parents had any siblings. The patient's maternal grandfather has had night blindness all his life, and the grandfather's grandmother had poor

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