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November 1957

The VitreousGross and Microscopic Observations Seen in Age and Disease, with Special Emphasis on the Role of Vitreous in Detachment of the Retina

Author Affiliations

New York
From the Institute of Ophthalmology of the Presbyterian Hospital.

AMA Arch Ophthalmol. 1957;58(5):725-734. doi:10.1001/archopht.1957.00940010745012

Introduction  There are relatively few studies of the vitreous found in the literature where emphasis is placed on the gross appearance. Many criticisms of existing studies have frozen further investigation of obvious pathologic changes seen clinically, macroscopically, and microscopically. De Wecker1 accurately described the process of vitreous shrinkage as well as the important relationship of the vitreous to detachment of the retina. Not until Gonin2,3 applied cautery to seal the retinal tears did the significance of vitreous changes in retinal detachments finally gain its relative importance.The normal vitreous is a transparent gel that completely fills the posterior part of the eye. In its normal state it acts as a cushion to help keep the structures of the eye in their normal position. The important function of cushioning the retina helps maintain the retina in contact with the pigment epithelium. In the young adult in whom there has

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