This section will be devoted to both macular and extramacular circinate lesions as seen in venous obstruction, diabetic retinopathy, Coats' disease, Leber's disease (multiple miliary aneurysms with retinal degeneration), and senile macular disciform degeneration. The various findings such lesions have in common will be noted, and a possible pathologic sequence in their formation will be suggested.
Jensen1 described circinate lesions seen after branch venous obstruction as a perimacular zone of white exudate separated from a central yellowish-gray discolored area. He thought these were rarely occurring secondary phenomena most frequently preceded by hemorrhage. Seventeen of his sixty-one cases of branch venous obstruction showed circinate infiltrates. Some appeared as early as two months after the obstruction. Later, as they became more fully developed and typical, the exudates coalesced and lobed figures were formed. These circinate figures were sharply outlined, varied in size, appeared singly or in groups, and were located
HOUSTON WR, WISE GN. Circinate RetinopathyPart II. AMA Arch Ophthalmol. 1957;58(6):783-796. doi:10.1001/archopht.1957.00940010805002