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April 1958

Corneal Changes from Quinone-Hydroquinone Exposure

Author Affiliations

Durham, N. C.; Kingsport, Tenn.
From the Division of Ophthalmology, Duke Hospital, and the Division of Industrial Hygiene, Tennessee Eastman Co.

AMA Arch Ophthalmol. 1958;59(4):495-501. doi:10.1001/archopht.1958.00940050051004

Staining of the cornea and conjunctiva, with precipitation of dark brown pigment granules within these tissues, is recognized as an industrial hazard for workers engaged in the manufacture of hydroquinone. In a previous report, submitted as a candidate's thesis to the American Ophthalmological Society, in 1946, one of us (B. A.) described certain characteristic lesions of the cornea and conjunctiva which had developed among a group of workers engaged in the manufacture of this chemical.1 These studies indicated that the severity of involvement was proportional to the length of exposure and was conditioned by the cleanliness, and possibly to some extent by the age, of the individual worker. Although there are now a constant awareness of the possibility of seriously disabling exposure and strict supervision of plant and personnel, the development of ocular lesions among workers in this industry remains a problem. One of the preventative measures adopted as

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