In previous publications it has been pointed out, on the basis of in vitro perfusion studies of enucleated eyes,3,4 that the depth of the anterior chamber exerts a very considerable influence on the facility of aqueous outflow. We believe that this fact is sufficiently important to warrant a more detailed discussion; at the same time we shall give the results of a systematic investigation into the influence of the pressure of the perfusion fluid on the facility of aqueous outflow.
I. The Influence of the Depth of the Anterior Chamber
From the very beginning of our experiments we have been struck by the fact that the aqueous flow is as a rule considerably more important in eyes with deep anterior chambers than in eyes with anterior chambers of less depth.This fact led us to begin experiments involving systematic modification of the depth of the anterior chamber by reducing
FRANCOIS J, RABAEY M, NEETENS A, EVENS L. Further Perfusion Studies on the Outflow of Aqueous Humor in Human Eyes. AMA Arch Ophthalmol. 1958;59(5):683-691. doi:10.1001/archopht.1958.00940060067007