Cataract associated with congenital ichthyosis is a rare occurrence. It is the purpose of this paper to discuss this occurrence, to review the literature available, and to present two cases occurring in Japanese male siblings.
The two cases were isolated instances in a family with no history of ichthyosis or cataract on either the paternal or maternal side. The parents of the children had written to relatives in Japan for further pertinent family history, with negative results, except that a maternal aunt had had skin trouble involving the face. There was no intermarriage in any of the relatives or parent consanguinity. Both children were healthy, normal, and well developed.
Ichthyosis is a congenital abnormality of cornification of the skin associated with dryness, scaliness, and warty growths.1 It is often familial and has a genetic background. It may not appear until a year or more after birth. The common variety,
PINKERTON OD. Cataract Associated with Congenital Ichthyosis. AMA Arch Ophthalmol. 1958;60(3):393-396. doi:10.1001/archopht.1958.00940080409007