The treatment of a blind eye with opaque media, but otherwise quiet and nonreactive, presents the ophthalmologist with a serious problem. He must decide whether the eye should remain and the patient be kept under observation or whether it should be enucleated because of possible danger of missing a hidden neoplasm. Complicating factors in arriving at a decision are the distress of many patients at the thought of losing an eye and the reluctance of the surgeon to take out an eye that is not a known cause of danger and substitute a prosthesis with its inherent shortcomings.
In an effort to provide more information on which to base such decisions, we have reviewed two series of cases at the Armed Forces Institute of Pathology: (a) One consisted of 1000 cases of intraocular malignant melanoma, in which were 212 eyes with opaque media (21.2%); (b) the other series consisted of
MAKLEY TA, TEED RW. Unsuspected Intraocular Malignant Melanomas. AMA Arch Ophthalmol. 1958;60(3):475-478. doi:10.1001/archopht.1958.00940080493020