The interest in this paper lies in the fact that the ophthalmologic literature reveals only vague and rare references to Horner's syndrome on a hereditary basis.
Duke-Elder,1 mentions only that "rare hereditary and stationary form has been observed" and refers to von Michel,2 1903, and Oppenheim,3 1905. There are many references to congenital Horner's syndrome, but only Oppenheim3 reports a case of a boy with typical Horner's syndrome whose mother showed the same findings. Calhoun4 describes a family with typical Horner's syndrome in a description of heterochromia iridis.
My patient was a 21/2-year-old child who was brought to the office for evaluation of a left ptosis. Examination revealed a ptosis of 3 mm. on the left, reduced size of the pupil, absence of sweating on the homolateral side, relative enophthalmos, and a blue iris on the left with a brown iris on the right. With
DURHAM DG. Congenital Hereditary Horner's Syndrome. AMA Arch Ophthalmol. 1958;60(5):939-940. doi:10.1001/archopht.1958.00940080959013