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Article
November 1958

OCULAR MANIFESTATIONS OF RILEY-DAY SYNDROME: FAMILIAL AUTONOMIC DYSFUNCTION

Author Affiliations

115 Bay State Road, Boston 15.

AMA Arch Ophthalmol. 1958;60(5):966. doi:10.1001/archopht.1958.00940080984020

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Abstract

To the Editor:  —I think it is obvious from the text of my paper that vitamin A deficiency was seriously considered as a possible cause of the keratopathy in the patient which I reported as Case 1. Dr. Cogan's clinical and pathologic impression was vitamin A deficiency. It was Dr. Berenberg's discovery that the child had Riley-Day syndrome rather than avitaminosis which stimulated me to make my report. Since the medical evaluation of the patient as a whole is obviously vitally important to the argument, I have asked Dr. Berenberg to comment on Dr. Rambo's letter.At my request, the Department of Pathology at the Massachusetts General Hospital recently reviewed the autopsy material in this case. Dr. William Thurlbeck, Pathologist, reports as follows:"Microscopically, there was no evidence of squamous metaplasia of the bronchi, renal pelves, or the intestine, despite multiple sections. The pancreas was noted as normal grossly, but

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