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December 1958

Cortical Blindness with Partial Recovery Following Acute Cerebral Anoxia from Cardiac Arrest

Author Affiliations

San Francisco; Baltimore

AMA Arch Ophthalmol. 1958;60(6):1061-1069. doi:10.1001/archopht.1958.00940081081012

Recently we have observed a patient who suffered cortical blindness as a result of cardiac arrest. Our studies on this patient have brought out some interesting features of this type of blindness and may serve to increase in some degree knowledge of the basic mechanisms underlying true cortical blindness as differentiated from blindness associated with more anterior involvement of the visual pathways. Cardiac arrest causes immediate catastrophic anoxia in the central nervous system. Anoxia of the cerebral cortex, regardless of the mechaanism, forms the basis for all conditions leading to cortical blindness, with the exceptions of direct trauma and invasion by tumor. Through the opportunity to work with Dr. Richard Lindenberg * we have been better able to understand the visual symptomatology of cardiac arrest as exemplified by our patient. It is generally well known that severe hypoxia produces cortical changes particularly in the gray matter of the cerebrum and specifically

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