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April 1959

Unilateral Retinitis Pigmentosa with Glaucoma

Author Affiliations

From the Department of Ophthalmology, University of Illinois College of Medicine, and Illinois Eye & Ear Infirmary.

AMA Arch Ophthalmol. 1959;61(4):626-630. doi:10.1001/archopht.1959.00940090628018

Retinitis pigmentosa or primary pigmentary degeneration of the retina almost always appears as a bilateral disease and very rarely as a unilateral process.

Pedraglia, in 1865, reported the first unilateral case, and 50 years later Leber could only find 14 cases in the literature. In subsequent reviews of the literature for "authentic" cases Biegelman,1 in 1931, could only find ten; Dreisler,2 in 1942, sixteen; Maeder and Muller,3 in 1950, sixteen; François and Verriest,4 in 1952, twenty-three, and François,5 in 1958, twenty-five. All of these authors added at least one case of their own.

The patient to be discussed is of interest because electroretinographic studies have been reported only in two cases4,6 and associated glaucoma has not been previously mentioned in unilateral retinitis pigmentosa.

Report of a Case  A 48-year-old white woman was first seen in 1939 for a routine eye examination. Other than the

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