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Article
December 1959

Differences in Ultrastructure of Normal Human and Rabbit Ciliary Epithelium

Author Affiliations

St. Louis
Fight for Sight Fellow of the National Council to Combat Blindness.; From the Departments of Ophthalmology, and Anatomy, and the Oscar Johnson Institute, Washington University School of Medicine.

AMA Arch Ophthalmol. 1959;62(6):952-955. doi:10.1001/archopht.1959.04220060024004
Abstract

Introduction  In a previous investigation (Holmberg, 1957), an extensive analysis of the ultrastructure of the nonpigmented epithelium in rabbit eyes was carried out. The material included both the normal structure and changes in the structure after inhibition of the secretion of aqueous humor by acetazolamide (Diamox). In order to find out the effect of acetazolamide on the structure of human ciliary epithelium, an analysis of the normal ultrastructure of this epithelium has been started. As there proved to be remarkable differences as compared to the rabbit material, a preliminary report of these differences seems to be justified.

Material and Methods  So far three enucleated human eyes have been examined. The eyes were enucleated because of a malignant melanoma in the posterior pole. No clinical signs of altered secretion of aqueous humor could be detected. The operations were performed under local anesthesia (retrobulbar injection of Xylocaine). Immediately after the enucleation 1%

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