Retinoschisis is a splitting of the retinal layers derived from the inner layer of the optic cup. The splitting generally occurs in the outer plexiform layer. This article presents findings in the cases observed with special reference to the clinical picture, differential diagnosis, management, and data available in the literature.
Between 1946 and 1956, 107 patients affected with senile retinoschisis were examined with the binocular indirect ophthalmoscope and scleral indentation.2,18 The most important clinical features of senile retinoschisis are detected by ophthalmoscopy (Fig. 1), which reveals interesting details in the inner layer of the retinoschisis. Fundus changes observed may be divided in three categories which represent three progressive stages of the disease. In its earliest stage, senile retinoschisis affects the extreme fundus periphery on the temporal side and most often in the inferotemporal quadrant. It first appears to be nothing more than an exaggeration of cystoid degeneration
SHEA M, SCHEPENS CL, VON PIRQUET SR. RetinoschisisI. Senile Type: A Clinical Report of One Hundred Seven Cases. AMA Arch Ophthalmol. 1960;63(1):1-9. doi:10.1001/archopht.1960.00950020003001