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February 1960

Experimental Tonometry and Tonography on Rabbits

Author Affiliations

San Francisco
From the Division of Ophthalmology, Department of Surgery, Stanford University School of Medicine.

AMA Arch Ophthalmol. 1960;63(2):201-211. doi:10.1001/archopht.1960.00950020203001

Clinical tonography has opened up wide areas of discussion in the ophthalmologic literature in recent years. A large number of authors have written about the contribution of clinical tonography to the problems of glaucoma.

Kornblueth and Linner6 initiated a technique of experimental tonography in rabbits in 1955. Comparatively few authors—Stone and Prijot,4,13,14 1955; Becker and Constant,8 Kitajima,36 1956; Cristiansson,33 de Carvalho,21 Waki, and Perkins,7 1958—have worked with it for research purposes. Recent experiments about belated consensual changes in rabbit eyes by Stone and Sears,14 have stimulated us to start an experimental series of our own, since findings regarding consensual changes in rabbit eyes seem varied and controversial. Tonography requiring the use of general anesthesia on rabbits is very time consuming. It appeared important to find out the practical limitations as well as the areas of useful application. Or, in other words:

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