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Article
February 1960

Intraocular Pressure of the Unanesthetized HenLack of Response to Acetazolamide

Author Affiliations

Uppsala, Sweden
From the Pharmacological Institute, University of Uppsala.; Author on leave of absence from the Wilmer Institute, Baltimore, Maryland.

AMA Arch Ophthalmol. 1960;63(2):212-216. doi:10.1001/archopht.1960.00950020214002
Abstract

For the last 50 years, the eyes of birds have rarely been the object of physiologic study. Although aqueous flow measurements of the same order of magnitude as in the rabbit and guinea pig have been reported for the domestic chicken by Bárány,1 avian intraocular manometry has not been studied. The present paper concerns the results of direct manometry of the anterior chamber of the unanesthetized hen and the failure of carbonic anhydrase inhibitors to reduce the intraocular pressure.

Method  One-year-old egg laying Rhode Island hens, weighing between 2 and 3 kg., were maintained on a diet of 92% grain, 6% meat powder, 2% ground limestone, and water ad lib. None of the hens studied had ocular evidence of fowl lymphomatosis. All experiments were performed on unanesthetized hens jacketed in a normal perching position. The head was immobilized by a clamp fitted with blunt end screw plugs which were

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