Leukoplakia is a precancerous lesion usually associated with the mucous membranes of the mouth or genitalia. In the eye, leukoplakia is thought usually to arise from the limbal conjunctiva in the temporal region.1 In Ash and Wilder's series of 93 limbal epithelial tumors, 13 were considered to be leukoplakia, but presumably, all were primary in the conjunctiva.2 The following case is presented because it appears to have arisen in grafted skin 16 years after the treatment for a particularly persistent recurrent pterygium.
A 72-year-old Jamaican woman was referred to the Gorgas Eye Clinic from a local dispensary on Sept. 24, 1957, because her son-in-law was concerned about the change in color of the corner of her left eye during the past three months. She stated that she had a growth removed from the left eye for the first time in 1929. The lesion reportedly recurred within two weeks.
McGLYNN LD, RUPP RH. Leukoplakia in Skin Grafted for Pterygium. AMA Arch Ophthalmol. 1960;63(2):313-314. doi:10.1001/archopht.1960.00950020315014