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The generalized and hereditary disorders of connective tissue are of peculiar interest to the ophthalmologist, who finds severe and often diagnostic changes in the eyes when these tissues are affected. Dislocation of the lens in the Marfan syndrome, blue sclera in osteogenesis imperfecta and the Ehlers-Danlos syndrome, angioid streaks in pseudoxanthoma elasticum, and the corneal opacification in Hurler's syndrome are sufficient examples to emphasize the need for an authoritative discussion of these peculiar diseases frequently identified by the ophthalmologist.
Although this book is not written for the ophthalmologist per se, a discussion of the clinical behavior of hereditary syndromes in general forms a valuable background for the ophthalmologist as well as for the general physician. A chapter on the biology of normal connective tissue brings us up to date on the advances in the chemistry of collagen and poses many intriguing questions which might direct ophthalmic research in these fields,
Heritable Disorders of Connective Tissue. AMA Arch Ophthalmol. 1960;63(5):905. doi:10.1001/archopht.1960.00950020907024