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January 1961

Note on the Electroretinogram in a Case of Macroglobulinemia and Some Forms of Anemia

Author Affiliations

Iowa City
From the Department of Ophthalmology, College of Medicine, State University of Iowa.

Arch Ophthalmol. 1961;65(1):111-113. doi:10.1001/archopht.1961.01840020113018

A case of macroglobulinemia with unusual fundus findings has recently been reported by Gates and Richards.1 This patient also presented severe electroretinographic changes which will be briefly described in this paper and compared to electroretinograms obtained from patients with various forms of anemia.

Report of Cases 

Case 1  —Electroretinograms were done on the patient with macroglobulinemia on Feb. 9, 1960, on which date he had a hemoglobin concentration of 9 gm. %. The electroretinographic records from either eye were essentially the same. They showed with I1 stimuli * after 12 min. of dark adaptation only a small negative deflection. With I1 F1.30 there was no response after 18 min. of dark adaptation and the responses with I1 F0.7 and I1 were extremely low. They consisted essentially of slight responses of the photopic mechanism. The relative intactness of the photopic mechanism was evidenced also by the

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