The availability of a laboratory animal with an open angle impairment of aqueous outflow would be most helpful to the further investigation of chronic simple glaucoma. The outflow facility can be determined either in the living or dead state, although in vitro measurements are a more certain indicator of organic change. An experimental decrease of outflow facility has been produced by Flocks et al.1 by an equatorial elastic band placed on the rabbit eye. The present study describes an in vitro decrease of the outflow facility by retrociliary diathermy of the globe or posterior angiodiathermy of the long posterior ciliary vessels.
Adult albino rabbits of either sex, from 2.5 to 3 kg. were used. Diathermy was done under general anesthesia with pentobarbital (Nembutal). The right eye was diathermied while the left globe served as a control. In several control rabbits neither eye was diathermied. The Castroviejo unit was
LEVENE RZ, BLOOMGARDEN C. Experimental Decrease of Aqueous Outflow in the Rabbit. Arch Ophthalmol. 1961;66(2):273-276. doi:10.1001/archopht.1961.00960010275020