Results of provocative testing in angle-closure glaucoma are presumed to depend on mechanical obstruction to the egress of aqueous.1,2 Recent refinements of this test have hinged on recording a reduction in outflow facility prior to any elevation in intraocular pressure.3-5 Several investigators have indicated that following mydriasis a reduction in outflow facility of 25%-30% is strongly suggestive of angle-closure glaucoma. It is the purpose of this communication to present evidence that elevation of intraocular pressure and reduction of out-flow facility may occur reproducibly in certain patients with wide, unencumbered angles.
Materials and Methods
Patients for this study were obtained from the Glaucoma Research Service of the New York Hospital-Cornell Medical Center. When our interest in this study became known, several patients with similar findings were referred for study by private ophthalmologists. In this manner 9 patients were obtained who clearly showed the reported effects. Three of these patients
GALIN MA. The Mydriasis Provocative Test. Arch Ophthalmol. 1961;66(3):353-355. doi:10.1001/archopht.1961.00960010355011