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The popularity of a topic may be measured by its frequency on the agenda of postgraduate seminars. By this criterion ocular fungus infection is now a popular topic, but this has come about only in recent years. After Birge's review in 1953, nine cases of fungus keratitis were reported within the next three years. This contrasts with the period following the report of the first case of keratomycosis in 1933 when only two cases were reported over an interval of nineteen years. The recent increase in keratomycoses has also been paralleled by a rise in reports of intraocular fungus infections.
The one clinical denominator in these recent cases has been the use of antibiotics and steroids. Antibiotics enhance fungus growth by inhibition of the normal bacterial flora while steroids facilitate fungus proliferation through interference with the host's anti-inflammatory and immune responses. The enthusiastic use of antibiotics and steroids has been
Makley TA. Ocular Fungus Infections. Arch Ophthalmol. 1961;66(4):456. doi:10.1001/archopht.1961.00960010458002