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In this monograph, A. C. Breebaart has considered the problem of corneal anaphylaxis. He has sought to correlate the work of Von Szily and Wessely, and others, with more recent experiments, particularly those of Morawiecki. To do this, the author has repeated the experiments of these investigators and has added others of his own. Based upon slit-lamp and histologic study of animal eyes, he has concluded that all forms of corneal anaphylaxis are the result of 2 components: (1) a diffuse progressive clouding of the cornea, which often is rapid in its development, and (2) a circumscribed oval avascular reaction. The latter includes Morawiecki's ring reaction. Breebaart has stressed the importances of the "postreactive state" of the cornea after the initial anaphylactic response (Wessely's phenomenon) to explain the variations in what is called "ring reaction."
The discussions of the literature and the bibliography are most comprehensive. Undoubtedly, some of Breebaart's
Experimental Corneal Anaphylaxis.. Arch Ophthalmol. 1962;67(2):272. doi:10.1001/archopht.1962.00960020274018