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To the Editor:
—I should like to call the attention of your readers to the fact that not infrequently patients on meprobamate (Equanil) have found that they have a loss of visual acuity for near objects. This occurs predominantly in individuals under the age of presbyopia and will last as long as these drugs are used.Two additional ocular findings, less frequent, and more usually occurring in the older age group, are, first, partial or complete loss of pupillary reaction to both light and convergence, and secondly, convergence insufficiency. We have found that 48 hours after the drugs have been stopped there is a recovery of their loss of accommodation to the normal.I am sure it is well known that patients taking belladonna by mouth and diethylstilbestrol by injection and also others on large doses of bromide will have a partial or complete paralysis of accommodation. I report this
Mayer LL. OCULAR EFFECTS OF MEPROBAMATE (EQUANIL). Arch Ophthalmol. 1962;67(2):274-275. doi:10.1001/archopht.1962.00960020276022