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To the Editor:
—Congratulations on your editorial in the November issue of the Archives of Ophthalmology entitled "Photosensitization and Cataracts"; it is most interesting. During the more than 12 years that we have marketed 8-methoxypsoralen (Oxsoralen), this office has refrained from commentary letters of any sort, since such remarks would likely be misconstrued as having commercial motives. But I personally feel your editorial directs attention to a serious problem in applying the results of animal studies, such as those discussed, to human medicine, when there is a wide difference in dosage and administrative technique between the rodent and routine clinical use in humans.
Elder TC, Elder PB. PHOTOSENSITIZATION WITH 8-METHOXYPSORALEN. Arch Ophthalmol. 1962;67(5):687. doi:10.1001/archopht.1962.00960020687032