The electroretinogram in color-blind individuals has been found to be abnormal by routine techniques only in achromats. In milder forms of color deficiencies, the results most often have been indicative of very slight alterations from the normal response. The reports by Heck and Rendahl,1,2 however, show clearly an alteration from normal in the form of the electroretinogram in the milder forms of color vision abnormality. They were able to demonstrate these changes in the response following adaptation to a colored light background. These alterations were found only in very small, relatively difficult to record, wavelets of the responses. Yonemura, in recent work, has also observed these wavelets.3
Because of the difficulties inherent in recording such small subcomponents of the electroretinogram with any degree of accuracy, little has been done with this observation. The advent of integrating computer techniques has allowed us to investigate this phenomenon more closely.
JACOBSON JH, SUZUKI T, STEPHENS G. The Electroretinogram Obtained by Computer Techniques in Color-Deficient Humans. Arch Ophthalmol. 1963;69(4):424-435. doi:10.1001/archopht.1963.00960040430003