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Article
November 1963

Glioma of the Optic Disk

Author Affiliations

San Francisco
Department of Ophthalmology, University of California Medical Center.

Arch Ophthalmol. 1963;70(5):648-650. doi:10.1001/archopht.1963.00960050650012
Abstract

Gliomas of the optic nerve are uncommon, although they are seen occasionally in patients with neurofibromatosis.1,2 Gliomas of the optic nerve at the disk have been reported,3 but they are most often found in the orbital portions of the nerve. Gliomas specifically of the optic disk and associated with neurofibromatosis have been reported in only three cases to date.4,5,6

Report of a Case  A white female patient of Spanish-American extraction developed grand mal seizures at the age of five months. They were controlled with phenobarbital and diphenylhydantoin sodium (Dilantin). When the patient was seven months old, movements of her left eye were abnormal and fixation was lost. At 11 months of age, a constant left esotropia was present and the child was referred to an ophthalmologist.

Family History.  —A 20-month-old sister had convulsive seizures, attributed to intracranial neurofibromatosis, and cutaneous signs (nodules and café-au-lait spots) of von

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