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Article
March 1964

CONGENITAL TOXOPLASMOSIS IN SIBLINGS

Author Affiliations

Syracuse, NY

Arch Ophthalmol. 1964;71(3):449-450. doi:10.1001/archopht.1964.00970010465031

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Abstract

To the Editor:  —Because of the importance of its implications, I do not believe that the letter by Dr. W. L. Hinrichs that appeared on page 927 of the October 24 issue of the Journal should go unanswered. I strongly support Dr. Castleman's statement, which is quoted by Dr. Hinrichs but with which he apparently is not in agreement. Dr. Langer's report, which Dr. Hinrich refers to, states that the same mother may produce Toxoplasma-infected infants in more than one pregnancy and, furthermore, that some women very often shed Toxoplasma. This seems to have attracted considerable acceptance, principally among nonworkers in the field. Some have even gone so far as to state that any pregnant woman with antibodies for Toxoplasma, or a positive skin test, should receive treatment with pyrimethamine (Daraprim) and sulfonamide to prevent the birth of a congenitally infected child. This is only to be condemned. In

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