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Dr. Loewenfeld's letter was referred to Drs. Jaeger, Weeks, and Duane, who offer the following reply:
To the Editor:
—Dr. I. Loewenfeld has presented her case. We are pleased she agrees that in the experiments described by us the defect is chiefly in the retinal portion of the afferent arc. The exact quote "the chief defect in the experiments described by them etc." is perhaps a Freudian slip.We readily admit that the pupillary sphincter—indeed the entire iris of a pressurized eye may be functioning abnormally. However, it is unlikely that experiments in cats and dogs with sustained increased intraocular pressure have much relevance to the transient conditions of our studies confined to humans. Nor do we believe the dilated pupil of glaucoma has much in common with our observations.We are not certain what "uncomplicated impairment of the afferent arc" means. If anisocoria is inherently excluded by definition, then
Jaeger EA, Weeks SD, Duane TD. ANISOCORIA DURING OPHTHALMODYNAMOMETRY-Reply. Arch Ophthalmol. 1964;71(3):452. doi:10.1001/archopht.1964.00970010466034