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Article
April 1964

Surgical Repair of the Syndrome of Epicanthus Inversus, Blepharophimosis and Ptosis

Arch Ophthalmol. 1964;71(4):510-516. doi:10.1001/archopht.1964.00970010526015
Abstract

The congenital anomaly of epicanthus inversus, blepharophimosis, and ptosis may occur sporadically, but it is a dominant characteristic in some families. I have seen several families in which we have been unable to trace the condition back from the generation in which it first appeared, but the majority of the offspring of this first generation have the anomaly. In one such family, all three children (males) of the first generation have the condition and to date all of their children also have it. The longest family history which I have been able to obtain covers four generations (Figs 1 and 2). It is reminiscent of, but unrelated to, mongolianism. All of my patients are of average intelligence.

The condition is characterized by a small skin fold which arises in the lower lid and runs upward and there is more or less lateral displacement of the inner canthi. The margin of

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