Human homograft techniques in ophthalmology are common today in the treatment of anterior ocular diseases, but relatively little has been written regarding the use of human sclera as a homograft material. Sclera is readily available from donor eyes, easily preserved for months, and almost universally accepted by the recipient. Human sclera, like cornea, is relatively avascular; thus hypersensitivity reactions have not been sufficient to cause rejection of the graft. As the principal ocular supporting structure, sclera is strong, yet flexible due to the triple coat of interwoven fibers. These factors make it applicable to use in any shape from a patch to an elongated strand.
Sclera has been used previously as a graft in the treatment of chronic scleromalacia perforans with impending rupture, as in our case description. It has served as a supporting sling in the posterior ectasia of high myopia (Borley1,2) and as a temporary or permanent
OBEAR MF, WINTER FC. Technique of Overlay Scleral Homograft. Arch Ophthalmol. 1964;71(6):837-838. doi:10.1001/archopht.1964.00970010853012