Two previous reports in this series1,2 described the fine structure of Bruch's membrane in the human, monkey, rabbit, guinea pig, and rat,1 in the cat and dog which have a tapetum cellulosum,2 and in the cow which has a tapetum fibrosum.2 The fine structure of Bruch's membrane in the macular area of the human eye is described in this paper. The frequency of macular choroidal disease in humans prompted this special study.
Materials and Methods
The material studied consisted of four eyes of humans 60 years old or older. The eyes were enucleated because of ocular melanomas, but their macular areas were intact.The method of processing these eyes was described in the first paper of the series.1 Pieces of choroid and attached retinal pigment epithelium were removed from the macular area by means of a trephine or razor blade and were then processed for
NAKAIZUMI Y, HOGAN MJ, FEENEY L. The Ultrastructure of Bruch's MembraneIII. The Macular Area of the Human Eye. Arch Ophthalmol. 1964;72(3):395-400. doi:10.1001/archopht.1964.00970020395018