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Article
May 1965

A Buried Corneal Implant Serving as a Barrier to Fluid

Author Affiliations

Boston
From the Corneal Research Unit, Institute of Biological and Medical Sciences, Retina Foundation, Boston City Hospital, and Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1965;73(5):635-639. doi:10.1001/archopht.1965.00970030637007
Abstract

Introduction  Knowles,1 utilizing the techniques of Bock and Maumenee,2 implanted plastic membranes in the intralamellar space of animal corneas. He found in rabbit and cat corneas that the stroma anterior to these membranes thinned and frequently degenerated. It was suggested that these findings were the result of pronounced drying and, consequently, these membranes functioned as barriers to water movement across the cornea.Maumenee3 implanted polypropylene membranes with 6 mm diameter into human corneas with bullous keratopathy in an effort to ameliorate the corneal edema. Subsequently, one of us (C. H. D.) implanted polypropylene membranes in seven cases of bullous keratopathy. It was observed that the cornea anterior to the membrane became less edematous and relatively transparent. The posterior portion of the stroma, however, became increasingly edematous and scarred. Therefore, it appeared that a buried corneal implant could be fashioned which would be a combination of the intralamellar

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