One of the more common causes of enucleation is the so-called blind, painful eye. Most of the eyes removed with this diagnosis have a previous history of trauma or surgery, following which the eye becomes blind. Later, the eye will develop episodes of pain which lead to its removal. The most common cause of these painful episodes is recurrent intraocular hemorrhage, but this is frequently not realized by the ophthalmologist. A number of factors are listed as possible causes for these episodes on the pathology sheets sent in with the eyes, the most common being glaucoma, iritis, and possible tumor. Hemorrhage is almost never listed as a possible diagnosis, so it was felt worthwhile calling attention to the frequency of this phenomenon.
The specimens received over a two-year period at the Estelle Doheny Eye Foundation were studied. In this period, there were 1,324 specimens of which 606 were globes. Of
RIFFENBURGH RS. Causes of the Blind, Painful Eye. Arch Ophthalmol. 1965;74(2):203-204. doi:10.1001/archopht.1965.00970040205014