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April 1966

Nodular Fasciitis of the Eye and AdnexaA Report of Ten Cases

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington.

Arch Ophthalmol. 1966;75(4):475-481. doi:10.1001/archopht.1966.00970050477006

Nodular fasciitis, a benign nodular proliferation of connective tissue involving the superficial fascia, has also been variously designated subcutaneous pseudosarcomatous fibromatosis, pseudosarcomatous fasciitis, and nodular fibrositis. Because of the clinical picture of a rapidly growing mass accompanied quite often by a rather alarming histologic appearance, the lesion has often been mistaken for a sarcoma.

The entity was first delineated in 1955 by Konwaler and co-workers,1 who described eight cases. In 1959, Sherwin and Friedell2 recorded two additional cases. Three reports appeared in 1960, one by Culberson and Enterline3 presenting five examples of nodular fasciitis; another by Kay4 that documented four more; and another by Stout5 that summarized the data from 77 cases studied in his laboratory. Despite Stout's very great experience with connective tissue tumors, no examples of this lesion had been located in his files before 1948. In 1961, two reports appeared, one by

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