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Article
April 1966

Antigenic Differences Between Anterior and Posterior Segments of the Bovine Uveal Tract

Author Affiliations

New York
From the Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York.

Arch Ophthalmol. 1966;75(4):526-534. doi:10.1001/archopht.1966.00970050528017
Abstract

Recently considerable interest in the autoimmune aspects of uveitis has stimulated studies in vitro of the antigenic properties of uveal tissue.1-6 All of these investigations used the entire uveal tract, that is, iris, ciliary body, and choroid combined, either as the immunizing agent or as the antigen used for testing serum antibodies. Clinically, however, a differentiation of uveitis into anterior, that is iritis or iridocyclitis, and posterior, that is choroiditis, has been well established. This nomenclature is used to clarify differences in the site of inflammation, and in many instances suggests a difference in the mechanism causing the inflammatory response. Iritis, or anterior segment inflammatory disease, is often considered to be of nongranulomatous origin, a term used to suggest that the inflammation is more likely of a sterile, hypersensitive origin than infectious. Choroiditis is usually classified in the presumptively granulomatous group of diseases, those caused by some foreign pathogenic

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