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Designating the case referred to as "Cancerous Melanosis" was based on the authority of Reese's text Tumors of the Eye, (ed 2, New York: Harper and Row). This text includes an artist's drawing of an almost identical case (Fig 7-85, p 338) captioned "Cancerous Melanosis."To call a lesion benign, precancerous, or cancerous is of great practical importance and requires clinical and histopathologic judgment which in the cases of melanomas is particularly difficult. Dr. Zimmerman presents pathologic criteria and Dr. Reese draws heavily on clinical experience in which he found 17% of those diagnosed as precancerous became cancerous in a follow-up of five or more years (Reese, A.B., and Morgan, W.E., Tumors of the Eye, ed 3, Washington: Butterworth Publishing Co., 1966).Whether the present case warranted exenteration, as was the clinical consensus a few years ago, or conservative observation as now recommended by Dr. Zimmerman, can be answered
Cogan DG. CRITERIA FOR MANAGEMENT OF MELANOSIS-Reply. Arch Ophthalmol. 1966;76(2):308. doi:10.1001/archopht.1966.03850010309026