The maculas of patients with chloroquine retinopathy exhibit a dramatic fluorescence when studied by intravenous fluorescein angiography. This fluorescence is interpreted as being due to a dysplasia of the macular pigment epithelium, which allows the underlying choroidal fluorescence to show through. We think that fluorescein fundus angiography is a new and valuable adjunct in the diagnosis and evaluation of chloroquine retinopathy.
KEARNS TP, HOLLENHORST RW. Chloroquine RetinopathyEvaluation by Fluorescein Fundus Angiography. Arch Ophthalmol. 1966;76(3):378-384. doi:10.1001/archopht.1966.03850010380016