In Norway we are not fully satisfied with the results obtained in our chronic open-angle glaucoma treatment. This may be due to the fact that 80% to 90% of our "primary" open-angle glaucomas also exhibit exfoliation syndrome ("pseudoexfoliation of the lens capsule").1-3 As suggested by Vogt,4 this type of glaucoma may be called glaucoma capsulare. It is usually classified as a secondary glaucoma, as exfoliative substance has been demonstrated in the intratrabecular spaces, probably interfering with the drainage of aqueous humor causing rise in intraocular pressure.5,6 A difference in trabecular meshwork pigmentation is found between primary open-angle glaucoma and glaucoma capsulare eyes, the latter being more heavily pigmented.7,8 A recent study by Tarkkanen9 indicates that a difference also may exist in prognosis.
It is well known that the incidence of exfoliation syndrome in patients with "primary" open-angle glaucoma is reported differently in different countries; ranging
HØRVEN I. Exfoliation SyndromeIncidence and Prognosis of Glaucoma Capsulare in Massachusetts. Arch Ophthalmol. 1966;76(4):505-511. doi:10.1001/archopht.1966.03850010507008