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March 1967

CoccidioidomycosisReport of a Case With Clinical Evidence of Ocular Involvement

Author Affiliations

Bethesda, Md
From the Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service, US Department of Health, Education, and Welfare, Bethesda. Dr. Green is presently at the Armed Forces Institute of Pathology, Ophthalmic Pathology Branch, Washington, DC; and Dr. Bennett is presently at the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda.

Arch Ophthalmol. 1967;77(3):337-340. doi:10.1001/archopht.1967.00980020339008

A 51-year-old Filipino male physician residing in Arizona developed disseminated coddidioidomycosis. After admission to the National Institutes of Health, he was noted to have many focal areas of active chorioretinitis in both eyes. The organism was cultured from the sputum, cerebrospinal fluid, and urine. The patient received amphotericin B by intravenous, intrathecal, and intraventricular routes. With this therapy the disseminated disease cleared and the chorioretinal lesions healed with a "punched-out" appearance and with varying degrees of hyperpigmentation at the borders.