Patients with unilateral and bilateral lid retraction of diverse etiologies were treated with topical sympatholytic agents. The agents produced a partial Horner's syndrome, resulting in a decrease in lid retraction and symptoms of exposure. No systemic side effects occurred.
Gay AJ, Salmon ML, Wolkstein MA. Topical Sympatholytic Therapy for Pathologic Lid Retraction. Arch Ophthalmol. 1967;77(3):341-344. doi:10.1001/archopht.1967.00980020343009