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Article
March 1967

Increased Intraocular Pressure and Optic Nerve Atrophy.

Arch Ophthalmol. 1967;77(3):423-424. doi:10.1001/archopht.1967.00980020425026

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Abstract

This book discusses a most important subject. The authors describe the normal vascular supply of the optic nerve. They find, contrary to the opinion of some, that the central retinal artery does not supply branches of significance for the nutrition of the optic nerve. This is supplied, they state, by the "central optic nerve artery" or "at least an equivalent system of axial blood supply to the optic nerve." The lamina cribrosa is supplied by (1) branches from the arterial circle of Zinn-Haller which originates from branches of the short ciliary arteries and (2) division of the axial system of the optic nerve.

The authors' histopathological studies suggest that the first tissue defect due to increased intraocular pressure is the development of small holes in the nerve fiber layer; the mesodermal tissue is then compressed and excavation of the disc results. Clinically the authors report cases of loss of visual

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