We believe this is the first report of a case of diffuse malignant melanoma of the iris arising in a patient with oculodermal melanocytosis (nevus of Ota).
A review of the literature revealed eight previously recorded malignant melanomas in the nevus of Ota.
Font RL, Reynolds AM, Zimmerman LE. Diffuse Malignant Melanoma of the Iris in the Nevus of Ota. Arch Ophthalmol. 1967;77(4):513-518. doi:10.1001/archopht.1967.00980020515014