[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.166.3.44. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
August 1967

The Efficacy of Combinations of Ocular Hypotensive DrugsA Tonographic Approach

Author Affiliations

Chicago
From the Department of Ophthalmology, University of Illinois, College of Medicine, Chicago.

Arch Ophthalmol. 1967;78(2):140-146. doi:10.1001/archopht.1967.00980030142006
Abstract

A tonographic study of one pilocarpine hydrochloride-physostigmine (eserine) salicylate combination did not disclose any evidence of additive effects. A study of several combinations of miotics with levo-epinephrine hydrochloride revealed truly additive effects, probably due to functional interaction of the drugs involved. The study suggests that epinephrine exerts its resistance-lowering effect by action on essentially the same section of the outflow channels as that influenced by the miotics.

×