A characteristic lesion of the cornea was found in six patients with rheumatoid arthritis and three patients with rheumatoid arthritis and Sjögren's syndrome. The lesions were marginal furrows usually in the inferior cornea. Four of the nine patients had bilateral involvement. The lesions could be superficial and stationary or could progress to marked thinning and perforation. Generally, inflammation and vascularization were minimal. Corticosteroid therapy was of no value and may have been harmful.
Brown SI, Grayson M. Marginal FurrowsA Characteristic Corneal Lesion of Rheumatoid Arthritis. Arch Ophthalmol. 1968;79(5):563-567. doi:10.1001/archopht.1968.03850040565011